We have the following situation: We are Using PL/SQL Developer (16.0.8) in an environment where multiple Oracle Full Clients are installed and we would like to use the latest Oracle Instantclient (23.26) in PL/SQL Developer. The issue here is: PL/SQL Developer uses the Primary Oracle Home from the Oracle Home Registry (set with Oracle Home Selector). The Instantclient is not in this registry and we don't want to remove the Oracle Home registry. We could configure PL/SQL developer to use the Instantclient, but for this we would need to change the PL/SQL Developer user settings or ensure that PL/SQL Developer is always started with the command-line parameter "InstantClient". Is there any other option? I was looking for an environment variable with an equivalent behavior like the "Instantclient" command-line parameter that we could set to override the Oracle client selection of PL/SQL Developer, but I was not able to find any.