The short answer:
fire up PLSD, right click on the procedure and select Test, in the Test window click on the Profiler button and then on the debug button. After the run is done click on the Profile tab to view the results
Note:
DBMS_Profiler package has to be available to the schema that you run this on. The package/proc/func has to be compiled with debug and maybe other things I'm not aware of since I run on a private DB as a privileged user.