Debugger loses connection

I have a problem at PL/SQL Developer that I need try execute debugger many times to work.
When I start the debugger the PL/SQL Dev has never work at the first execution, I wait at least 5 minutes for him and I break.
It works sometimes. Today, for example, the problem is occuring more frequently.
Many users at my work reported the same problem.

Please, give me the solution.
 
To obtain some more diagnostic information, can you modify the shortcut and add the DebugSQL parameter? For example:

"C:\Program Files\PLSQL Developer\plsqldev.exe" DebugSQL

Reproduce the problem and send me the debug.txt file that is generated in the PL/SQL Developer directory or in the %APPDATA%\PLSQL Developer directory (e.g. C:\Users\\AppData\Roaming\PLSQL Developer).
 
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