When I have a query like "select t.*, t.rowid from schema.table t where ..." and I click the lock icon to allow changes, it seems like the time to when row lock is acquired and I can actually edit data is much slower than in version 11.
It performs the exact same actions though. To obtain some more diagnostic information, can you modify the shortcut and add the DebugSQL parameter? For example:
Reproduce the problem (click on the lock icon) and send me the debug.txt file that is generated in the PL/SQL Developer directory or in the %APPDATA%\PLSQL Developer 12 directory (e.g. C:\Users\\AppData\Roaming\PLSQL Developer 12).