You can use the 'Desktop' command line option. I have several shortcuts for different databases just for this purpose. For instance, I have one shortcut with 'Desktop=Sandbox'. At he end of the day I just close PLD and the next day all windows are back there again.

At one point this saved hours of work when they cloned the dev database during my sick leave........

@Marco: as an aside, I seem to recall that at one point I could see my desktop name in the main window. However, I can't seem to make it show. Either I've done something wrong, or my memory is failing me. In the latter case, can you add this as an option in the upcoming release?

Thanks in advance,
Marco van der Linden